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Traitement cardiaque d'un adolescent par cellules souches

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Author/Contributor: UPI Medical Correspondent
Source: Science & Technology Desk
Published: March 5, 2003

In the first procedure of its kind in the world, Michigan doctors said Wednesday they have treated a teenage boy who suffered a heart attack with stem cells in hopes of repairing his damaged heart.

It’s still too early to tell if the procedure will generate new heart tissue, but the boy’s heart function has improved slightly since the procedure was performed two weeks ago, so it’s promising that maybe this is going to work. Dimitri Bonnville, 16, suffered a massive heart attack in February after being shot with a nail gun. Bonnyville’s heart was severely damaged and some of the tissue had died. His only option was a heart transplant.

In a bit of good fortune, doctors at Beaumont Hospital were developing a study protocol to treat older patients with heart problems with adult stem cells. The cells, which originate in the bone marrow “can turn into cells that are blood vessels and muscles so it’s perfect for the heart because we need both” said Grines, the author of the study protocol.

“When Dimitri came in, we thought he might be a good candidate for this,” she said. Bone marrow stem cells have been used to treat certain forms of cancer and other conditions but their use in treating heart conditions is still experimental – something like this has never been done before.

The young man’s condition ultimately would have led to heart failure.

An assessment of his heart function two weeks after the procedure found indications of improvement. Dimitri has since been discharged from the hospital and is able to carry out normal daily activity. Doctors will continue to assess Dimitri every three months. If there is going to be a benefit, they expect to see some indication of it by three months.